Chemical structures and biological activities of rhamnolipids produced [An article from: Bioresource Technology]

This digital document is a journal article from Bioresource Technology, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
The aim of this work was to study chemical structures and biological activities of rhamnolipids produced by Pseudomonas aeruginosa B189 isolated from milk factory waste. The culture produced two biosurfactants, a and b, which showed strong activity and were identified as l-rhamnopyranosyl-l-rhamnopyranosyl-@b-hydroxydecanoyl-@b-hydroxydecanoate or Rha-Rha C"1"0-C"1"0 and l-rhamnopyranosyl-l-rhamnopyranosyl-@b-hydroxydecanoyl-@b-hydroxydodecanoate or Rha-Rha C"1"0-C"1"2, respectively. Both compounds exhibited higher surfactant activities tested by the drop collapse test than several artificial surfactants such as SDS and Tween 80. Rhamnolipid a showed significant antiproliferative activity against human breast cancer cell line (MCF-7) at minimum inhibitory concentration (MIC) at 6.25@mg/mL while rhamnolipid b showed MIC against insect cell line C6/36 at 50@mg/mL.