This historic book may have numerous typos, missing text, images, or index. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. 1921. Not illustrated. Excerpt: ... CHAPTER XXII CASES M. M. Seventeen years of age. Menstruation at 15^ years, at intervals varying from 11 months to 8 weeks. Has had whooping cough, measles when 8 years old, chickenpox at 10 years,--all slight. Complaint: Pain on the right side for 6 months, and a full feeling in the stomach after eating. Rectal examination: A very small uterus, not much larger than a thumb, much nearer the symphysis than normal; unusually long utero-sacral ligaments. The patient is of slight build, a brunette, physically active, and a very bright student at college. Therapy: Ovarian extract 5 grs, thyroid extract 1/10, pituitary posterior 1/3. Therapy began June 17, 1919. The patient menstruated once in August freely and once in October, but noted that she is constipated since taking the prescription. For the next few months the pituitary posterior was omitted and ovarian residue was administered. No menstruation since then. April 29, 1920. Blood pressure 100. June 10th. Blood pressure 100. The white line on scratching of the skin was marked, turning red only very slowly. Therapy: Ovarian extract 5 grs., thyroid 1/10 gr., pituitary posterior 1/3 gr. June 17th. Patient complains that after taking the above prescription she had for two days and for the first time in her life frontal headaches. The pain in the right side has recurred. She notices again that she is constipated from taking the above prescription. This last change was likewise noted when the same medication was prescribed in June, 1919. Scratching of the skin causes a white line, which quickly becomes red. Rectal examination: Uterus of the same size as at first examination; left ovary very small; right ovary larger and nodular, and sensitive. In my experience the most difficult field for endocrine therapy li...