Finally, Lyon and Gorner have written a book that deals with the most profound and compelling implications of this work: gene therapy, or the possibility of bypassing symptoms of diseases by dealing instead with their root genetic. Although this well-researched and comprehensive volume might be a bit much for the casual reader, it is a masterful and colorful work filled with facts, personalities, and politics that would appeal to anyone with a real interest in understanding the history -- and possible futures -- of gene therapy.