Exploration and Analysis of DNA Microarray and Protein Array Data (Wiley Series in Probability and Statistics)

The emergence of genomics, the study of genes, is one of the major scientific revolutions of this century. Microarrays, a method used to analyze numerous DNA samples rapidly, enables scientists to make sense of this mountain of data using statistical analysis. They are being used in such areas of biomedical research as studying patterns for gene activity that cause cancers to spread. This book presents a comprehensive methodology for analyzing DNA microarray and protein array data. The most comprehensive treatment of this important emerging field, Exploration and Analysis of DNA Microarray and Protein Array Data includes: A review of basic molecular biology and a chapter introducing microarrays and their preparation Chapters on processing scanned images, preprocessing microarray data, group comparative experiments, and other designs Discussions of clustering, protein arrays, and applications for diagnostic tools Ample exercises assist absorbtion