Fly Pushing: The Theory and Practice of Drosophila Genetics

Experiments with Drosophila give investigators the chance to combine molecular and genetic approaches in studies of gene expression, cell function, and development. Fly genetics has a large and complex folklore that, for the uninitiated, is quite daunting. In this eagerly awaited book, Ralph Greenspan provides a bridge to that folklore. Entertaining and lucid, he guides the reader carefully through the practicalities of making crosses, isolating variants, mapping genes, constructing specific genotypes, and analyzing mutations. No previous knowledge of fly genetics is assumed. The techniques used are illustrated, and practice problems and solutions are included to assist the reader. This is an affordable and uniquely valuable book, ideal for graduate students starting projects and established investigators considering new avenues. A must for both personal and laboratory libraries.