Systematic Reviews in Pain Research: Methodology Refined

- Explains how to interpret systematic reviews and meta-analyses that estimate the efficacy and harm of pain relief interventions
- Describes what we have learned from systematic reviews and explores ways we can improve future trial design
- Outlines the practical relevance of trial outcomes in research on management of acute, chronic and cancer pain
- Explores the issues surrounding placebo controls in clinical trials
- Written and edited by experts on evidence-based critical care, anesthesia, and pain management