Sigma-RBI Handbook of Receptor Classification and Signal Transduction, 5th Edition

General description The expanded 5th edition presents concise information on the characterization and classification of a wide range of receptors, ion channels, transporters, neurotransmitter synthesis/metabolism pathways and intracellular signaling enzymes. In addition to updating and revising over 80 previous handbook entries, 26 new entries have been added with a strong focus on kinases and ion channels. Each peer-reviewed entry consists of an easy-to-read and up-to-date overview of the available information in the area, as well as a list of 12 key references to guide both the new investigator and the experienced researcher in their searches and reviews of the current literature. Each entry includes a table that presents the currently accepted classification of a given receptor, ion channel, enzyme or transporter into its component subtypes and subgroups. It also highlights the pharmacological tools with which to investigate their function and regulation.