NERDS: Book Three: The Cheerleaders of Doom / Michael Buckley

The NERDS series combines the excitement of international espionage with the awkwardness of elementary school as it follows the adventures of a group of unpopular fifth graders who run a spy network from inside their school. With the help of cutting-edge science, they transform their nerdy qualities into incredible abilities, and the results are awesome, inspiring and hilarious.
This third installment in the series stars Matilda Wheezer Choi, the asthmatic who can fly and kick butt courtesy of her nanobyte-enhanced inhalers. Matilda loves pro wrestling and hates anything girlie. Unfortunately for Wheezer, when a former-NERD-turned-villain gets extensive plastic surgery in order to become a cheerleader, Matilda must swallow her pride to successfully infiltrate the squad. The villain with pom-poms, Gerdie Baker, has created a device that opens portals to other worlds, and if Matilda doesn t find a way to destroy it, the fates of all the worlds will be at stake.

Praise for NERDS: The Cheerleaders of Doom
Fans of the series will gladly recognize how the mayhem of the plot is well matched by a surfeit of quips and general goofiness of the highest order Booklist

This series has gotten better with each book and I can't recommend it highly enough. Book Dads blog