Lipid and Protein Traffic: Pathways and Molecular Mechanisms (NATO ASI Series / Cell Biology)

This volume focusses on new developments in the field of membrane dynamics, in particular on the insertion and translocation of proteins, on intracellular protein, lipid and membrane traffic and sorting, and on the mutual interactions between the various events occurring during membrane biogenesis. Mitochondrial biogenesis, chloroplast assembly and the insertion of proteins into peroxisomes are highlighted. Toxins acting both from the intracellular as well as from the outside on membranes are treated including the effects of these compounds on membrane pores, channels and conductance. Lipid structure and function are discussed in relation to protein insertion into and translocation through membranes and the mechanisms underlying intracellular sorting and trafficking of specific phospholipids are elucidated.