Cost Rationalization in Pharmaceutical Production

The pharmaceutical industry is facing increasing pressure to reduce costs, in order to remain competitive. This can be achieved through a variety of ways like cost reduction through sustainable manufacturing strategies, developing a streamlined and consistent global supply network, identifying global suppliers and controlling COGS throughout the product development and manufacturing lifecycle. With low-cost manufacturing, high-quality research and manufacturing facilities and educated personnel, the Indian pharmaceutical industry presents both a competitive threat and partner opportunities. This has resulted in increasing its manufacturing capability to competetive international levels, so that it is fast emerging as a sourcing partner for international pharma majors. India now has the largest number of US FDA approved plants outside the USA and boasts of permanent facilities of USP and US FDA due to the large number of regulated pharma manufacturing facilities. This book for the first time provides a rare insight into the nitty-gritty workings of Indian pharma companies, how they have managed to bring down the cost of manufacturing to surprisingly low levels while maintaining compliance with world regulatory authorties. With the unique angle of supply chain opportunities, this book provides a scientific study of cost rationalization in production giving numerous examples, case studies, tables/charts and illustrations. Pharmaceutical companies worldwide can now tap into the management resources of Indian pharma companies for obtaining unique cost leverage and control cost of production. This is a very focussed and coincise book dealing exclusively for the first time on cost rationalization in pharmaceutical production through the route of supply chain gaps and opportunities. CONTENTS MANUFACTURING OPERATIONS RATIONALIZATION Batch Size Optimization, Conventional Formulation, Alternate Formulation for Manufacturing Flexibility, Suggestions for Future Research, Batch Size Determination Practical Issues, Make to Stock Items (MTS), Make to Order Items (MTO), Relationship Between Batch Size and Cycle Time, Current Practices in Pharma Industry, Production Process, Software for Optimization in Manufacturing, Heuristic for Improving Utilization of Module Type of Production Systems, Other Concepts for Manufacturing Optimization, How to Align Manufacturing to Demand? Conclusions, Other Ideas in Manufacturing, Yield improvement, Design for Manufacturability, Packaging Materials SKUs Proliferation, Japanese Way to US Market, References, WORKING CAPITAL RATIONALIZATION Cost Reduction Concepts, Common Excipients, Optimization of Service Levels, Procurement Strategies for MRO Items, Streamlining of MRO Purchases, Constituents of Inventory Turns Which One to Improve?, Inventory Turns A Relook, Cycle Stock, Safety Stock, Working Capital Concepts, MARKETING OPERATIONS RATIONALIZATION Finished Goods Inventory Planning, Controlling Selling, General and Administrative Expenses, Market Share Gaining Model, Organization Design for Selling Process, Judging Marketing Productivity, R & D OPERATIONS RATIONALIZATION Synergy Among the Medical and Pharmaceutical Sciences, Whether supply chain techniques can help in this regard? Intellectual Property Issues, QA Related Issues, PROJECT MANAGEMENT Successful Project Implementation, Optimizing Project Costs, Total Cost of Ownership, Cost Optimization, Product Planning for New Facilities to be Created,