Pavlovian-instrumental transfer of the discriminative stimulus effects of nicotine and ethanol in rats.: An article from: The Psychological Record
Book Details
Author(s)Joseph R., II Troisi
PublisherThomson Gale
ISBN / ASINB000MTDNXK
ISBN-13978B000MTDNX2
AvailabilityAvailable for download now
Sales Rank99,999,999
MarketplaceUnited States 🇺🇸
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This digital document is an article from The Psychological Record, published by Thomson Gale on September 22, 2006. The length of the article is 5674 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.
From the author: To date, only 1 study has evaluated the impact of a Pavlovian drug conditional stimulus (CS) on operant responding. A within-subject operant 1-lever go/no-go (across sessions) design was used to evaluate the impact of Pavlovian contingencies on the discriminative stimulus effects of nicotine (0.4 mg/kg) and ethanol (800 mg/kg) in male Sprague Dawley rats. Drugs were administered 10 min before each acquisition and test session. One drug predicted sessions of food reinforcement and the other drug predicted sessions of nonreinforcement; stimulus roles were counterbalanced. In Experiment 1 (n = 7), operant lever pressing was initially maintained on a VI-30 s schedule of food reinforcement. This phase was followed by 20 (CS+ vs. CS-) Pavlovian drug discrimination training sessions without the levers present. Two extinction tests revealed significantly more operant lever pressing under the CS+ drug conditions compared to the CS- drug conditions, suggesting evidence for Pavlovian-instrumental transfer. Operant training significantly strengthened stimulus control. In Experiment 2 (n = 7), the drugs functioned as operant drug discriminative stimuli first. Next, the predictive roles of the drug [S.sup.D]s and [S.sup.[DELTA]]s were reversed under Pavlovian CS- and CS+ contingencies, respectively. The original stimulus control was significantly undermined but was not reversed. These studies suggest that Pavlovian drug-reinforcer contingencies embedded within the operant 3-term contingency may play a partial role in mediating the discriminative stimulus effects of drugs.
Citation Details
Title: Pavlovian-instrumental transfer of the discriminative stimulus effects of nicotine and ethanol in rats.
Author: Joseph R., II Troisi
Publication:The Psychological Record (Magazine/Journal)
Date: September 22, 2006
Publisher: Thomson Gale
Volume: 56 Issue: 4 Page: 499(14)
Distributed by Thomson Gale
From the author: To date, only 1 study has evaluated the impact of a Pavlovian drug conditional stimulus (CS) on operant responding. A within-subject operant 1-lever go/no-go (across sessions) design was used to evaluate the impact of Pavlovian contingencies on the discriminative stimulus effects of nicotine (0.4 mg/kg) and ethanol (800 mg/kg) in male Sprague Dawley rats. Drugs were administered 10 min before each acquisition and test session. One drug predicted sessions of food reinforcement and the other drug predicted sessions of nonreinforcement; stimulus roles were counterbalanced. In Experiment 1 (n = 7), operant lever pressing was initially maintained on a VI-30 s schedule of food reinforcement. This phase was followed by 20 (CS+ vs. CS-) Pavlovian drug discrimination training sessions without the levers present. Two extinction tests revealed significantly more operant lever pressing under the CS+ drug conditions compared to the CS- drug conditions, suggesting evidence for Pavlovian-instrumental transfer. Operant training significantly strengthened stimulus control. In Experiment 2 (n = 7), the drugs functioned as operant drug discriminative stimuli first. Next, the predictive roles of the drug [S.sup.D]s and [S.sup.[DELTA]]s were reversed under Pavlovian CS- and CS+ contingencies, respectively. The original stimulus control was significantly undermined but was not reversed. These studies suggest that Pavlovian drug-reinforcer contingencies embedded within the operant 3-term contingency may play a partial role in mediating the discriminative stimulus effects of drugs.
Citation Details
Title: Pavlovian-instrumental transfer of the discriminative stimulus effects of nicotine and ethanol in rats.
Author: Joseph R., II Troisi
Publication:The Psychological Record (Magazine/Journal)
Date: September 22, 2006
Publisher: Thomson Gale
Volume: 56 Issue: 4 Page: 499(14)
Distributed by Thomson Gale
