Enhancement of a conducting polymer-based biosensor using carbon [An article from: Analytica Chimica Acta]

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Description:
A biosensor with improved performance was developed through the immobilization of horseradish peroxidase (HRP) onto electropolymerized polyaniline (PANI) films doped with carbon nanotubes (CNTs). The effects of electropolymerization cycle and CNT concentration on the response of the biosensor toward H"2O"2 were investigated. It was found that the application of CNTs in the biosensor system could increase the amount and stability of the immobilized enzyme, and greatly enhanced the biosensor response. Compared with the biosensor without CNTs, the proposed biosensor exhibited enhanced stability and approximately eight-fold sensitivity. A linear range from 0.2 to 19@mM for the detection of H"2O"2 was observed for the proposed biosensor, with a detection limit of 68nM at a signal-to-noise ratio of 3 and a response time of less than 5s.