![Cytotoxicity in the marine dinoflagellate Prorocentrum mexicanum from Brazil [An article from: Comparative Biochemistry and Physiology, Part C]](https://www.ebooknetworking.net/books/B00/0RR/bigB000RR8FTO.jpg)
Cytotoxicity in the marine dinoflagellate Prorocentrum mexicanum from Brazil [An article from: Comparative Biochemistry and Physiology, Part C]
Book Details
PublisherElsevier
ISBN / ASINB000RR8FTO
ISBN-13978B000RR8FT8
AvailabilityAvailable for download now
Sales Rank99,999,999
MarketplaceUnited States 🇺🇸
Description
This digital document is a journal article from Comparative Biochemistry and Physiology, Part C, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.
Description:
The microscopic algae in the oceans are crucial food for filter feeding bivalve shellfish (oysters, mussels, scallops, clams, etc.) as well as for the larvae of commercially important crustaceans. Some species of microalgae have the capacity to produce potent toxins, such as saxitoxins and ciguatoxins, which may intoxicate humans. Among the marine phytoplankton, the dinoflagellates are the main toxin producers. Studies on the marine phytoplankton from the Sao Sebastiao Channel, southeastern coast of Brazil, showed a great diversity of dinoflagellates. Some species were collected and cultured at the Marine Biology Center of the Sao Paulo University (USP). The polar (PEs) (aqueous) and apolar (AEs) (methylene chloride) extracts of the cultivated dinoflagellate species were tested on different stages of the sea urchin development, on mouse erythrocytes and on microfilaments organization in a neuroblastoma cell line. Prorocentrum mexicanum PE and AE induced cells anomalies and cell division inhibition of sea urchin eggs at EC"5"0 of 78.75 @mg/mL (95% CI from 32.56 to 190.50) and 22.50 @mg/mL (95% CI from 2.96 to 170.80) respectively (n=3). Both AE and PE of P. mexicanum induced hemolysis with EC"5"0 of 65.07 @mg/mL (95% CI from 27.40 to 154.60) and 84.29 @mg/mL (95% CI from 53.26 to 133.40 @mg/mL), respectively. P. mexicanum PE was tested in immunofluorescence for actin filaments organization in neuroblastoma cultured cell.
Description:
The microscopic algae in the oceans are crucial food for filter feeding bivalve shellfish (oysters, mussels, scallops, clams, etc.) as well as for the larvae of commercially important crustaceans. Some species of microalgae have the capacity to produce potent toxins, such as saxitoxins and ciguatoxins, which may intoxicate humans. Among the marine phytoplankton, the dinoflagellates are the main toxin producers. Studies on the marine phytoplankton from the Sao Sebastiao Channel, southeastern coast of Brazil, showed a great diversity of dinoflagellates. Some species were collected and cultured at the Marine Biology Center of the Sao Paulo University (USP). The polar (PEs) (aqueous) and apolar (AEs) (methylene chloride) extracts of the cultivated dinoflagellate species were tested on different stages of the sea urchin development, on mouse erythrocytes and on microfilaments organization in a neuroblastoma cell line. Prorocentrum mexicanum PE and AE induced cells anomalies and cell division inhibition of sea urchin eggs at EC"5"0 of 78.75 @mg/mL (95% CI from 32.56 to 190.50) and 22.50 @mg/mL (95% CI from 2.96 to 170.80) respectively (n=3). Both AE and PE of P. mexicanum induced hemolysis with EC"5"0 of 65.07 @mg/mL (95% CI from 27.40 to 154.60) and 84.29 @mg/mL (95% CI from 53.26 to 133.40 @mg/mL), respectively. P. mexicanum PE was tested in immunofluorescence for actin filaments organization in neuroblastoma cultured cell.
