Correlation Analysis in Organic Chemistry: Introduction to Linear Free-Energy Relationships

In this book the author has set out to show the variety of applications of correlation analysis to a wide range of chemical and related sciences. The author has assumed that readers have a basic knowledge of organic chemistry: nomenclature, characteristic reactions of the common functional groups, reaction mechanisms, and electornic theory. A good grounding in physical chemistry is also assumed: valency theory, kinetics, equilibria and spectroscopy but brief introductory accounts of some topics are given where these may be helpful. No previous knowledge of enzymology or pharmacology is assumed. Contents- Introduction and genral survey: what is correlations analysis? Terminology for substituent effects. Symbols The Hammett Equation The Separation of polar, steric and resonance effects Applications to spectroscopy Solvent effects The effect of the reagent on reactivity Some biological effects of organic reactivity Answers to problems