Reversibility in Testicular Toxicity Assessment

A number of endpoints of testicular toxicity have been studied, including those involving the germ, Sertoli, and Leydig cells and the testicular vasculature, but there has been little work done regarding the reversability of such effects. Theoretical considerations and empiric observations suggest that reversibility may be an important parameter to consider in the evaluation of male reproductive toxicity. This book considers these possibilities, providing an authoritative summary of knowledge. Reversibility in Testicular Toxicity Assessment is organized by testicular element and will provide an important reference source for toxicology researchers and reproductive medicine clinicians involved with reproductive toxicity.