New to the Second Edition—
· Advances in the application of NMR spectroscopy and mass spectrometry, bioactive chemical detection and extraction, dereplication, and novel bioassay development
· New case studies and illustrations that demonstrate the practical applications of specific techniques
· A group of new contributors presenting research from their own laboratories that emphasize both the philosophy and rationale behind detection, isolation, and structural determination
Following an overview of natural product chemistry techniques and approaches, many new chapters discuss selection of source material, quantitative NMR, high speed counter-current chromatography, dereplication of extracts, and methods to determine the stereochemistry of bioactive natural products. Examinations of new technologies including LC-NMR, biosensors, and biofingerprinting accompany discussions on the search for specific activities in anticancer and antimalarial applications, seed germination stimulation, and mammalian toxicity.
With the participation from active researchers, this definitive work supplies a vital extension and an enduring contribution to the science and art of bioactive natural product detection, isolation, and structural determination.