Over forty of Crumb's peers, friends, and admirers have contributed to this work, including:
-Simpsons creator Matt Groening on cross-hatching and the corruption of youth
-Filmmaker Terry Gilliam on pre-Monty Python days with Crumb and Mad creator Harvey Kurtzman
-Prankster Paul Krassner on the "slimy tentacles of our national id"
-Writer Alan Moore's infatuation with Angelfood McSpade
-Notes on Crumb's sexual obsessions by Screw magazine publisher Al Goldstein
-First wife Dana Crumb on the rise and fall of their marriage
-Filmmaker Jim Jarmusch's quixotic effort to canonize Crumb
-Crumb's warning to Reverend Ivan Stang about selling out
-Film critic Roger Ebert and Terry Zwigoff on the making of the harrowing Crumb documentary
And, naturally, appreciations, criticisms, stories of debauchery and foolishness from such noted comix artists as Daniel Clowes, Will Eisner, Peter Kuper, S. Clay Wilson, Doug Allen, Bill Griffith, Spain, the Friedman Brothers, Trina Robbins, Jim Woodring, Mary Fleener, Frank Stack, and Kim Deitch.