Antibiotics I (Japanese Technology Reviews)

This volume reviews recent studies on antibiotics in Japan. ss\n-Lactams and other antimicrobial agents are described, with particular emphasis given to oral cephalosporins, and parenteral cephems and related compounds pertaining to compound synthesis, drug efficiency, oral absorption, and physicochemical and biochemical properties. Second and third generation cephalosporins and major ss\n-lactam antibiotics developed in Japan are examined. Also discussed are nonclassical ss\n type antibiotics -\n penems, carbapenems and monobactams -\n in addition to aminoglycosides and macrolides. This book provides a major contribution to the study of antibiotic structure -\n activity relationships based on recent research findings, and will serve as a useful reference to academics and researchers in the fields of anitbiotic design and synthesis, drug delivery, drug mechanisms and efficacy, biochemistry and microbiology.