THz Spectroscopy of Biomolecules: Reactive Molecules and Hydration Dynamics ofBiomolecules Investigated byTHz Spectroscopy

Life is water dancing to the tune of macromolecules" stated Albert Szent-Gyorgyi medicine Nobel Prize winner in 1937. Proteins can influence their hydration water dynamics and structure. Conversely water molecules can control the shape and function of proteins and consequently also the cell biology and metabolism. Hydration dynamics can be a regulator for cell activity and can even shut down cell metabolism completely under extreme conditions. The author shows that proteins and their hydration water molecules highly influence each other their motions are coupled. The result is a dynamic interplay a dance to the same tune at terahertz frequencies of high importance to the cell and life in general."