Review of ESPS-2: Prevention of Secondary Stroke and Transient Ischemic Attack Using Aspirin and Extended-Release Dipyridamole (Postgraduate Medicine Book 121)

Abstract: Original article Diener HC, Cunha L, Forbes C, Sivenius J, Smets P, Lowenthal A. European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. J Neurol Sci. 1996;143(1–2):1–13. PRACTICE PEARL The ESPS-2 showed that the combination of low-dose ASA (25 mg bid) and ER-DP (200 mg bid) provided an additive benefit for the prevention of recurrent stroke and TIA over monotherapy with either ASA or ER-DP.