Cell Cycle Effects of Drugs (International Encyclopedia of Pharmacology and Theraputics)

An understanding of the mechanism of action of anticancer agents depends on investigations into the cell cycle effects of these agents. The intent of this volume is to review our current knowledge about these basic cell cycle effects and suggest what directions future investigations should take. Chapters 1 and 2 are general, basic chapters dealing with the biology of the cell cycle per se and quantitative cytokinetics (techniques) respectively. The remaining nine chapters each cover a specific anticancer compound as examples of various classes of anticancer agents. In bringing this information together for the first time this volume represents a major step in the understanding of the mechanisms that are involved in the treatment of cell cycle disorders.