Guidebook to the Secretory Pathway (Sambrook & Tooze Guidebook Series)

The late 1970s and early 1980s saw a boom in research establishing molecular details related to secretory protein modifications such as signal peptide processing, proenzyme proteolytic maturation, glycosylation, and oligosaccharide modification. This timely new resource compiles what is known about the secretory pathway. The book charts how much of the current progress in the field derives from the development of cell-free systems that reproduce individual transport steps, the identification of proteins associated with vesicular carriers, and the isolation of mutants and characterization of gene products that mediate protein translocation and secretion. Guidebook to the Secretory Pathway will be invaluable to researchers and students of cell and molecular biology.