Protein-Ligand Interactions: Structure and Spectroscopy (Practical Approach Series)

The two Practical Approach volumes on protein-ligand interaction do not comprise a comprehensive compilation of all the methods that can be used to investigate protein-ligand interactions. Instead, they are a selection of the most useful and easily applied methods and will be an invaluable guide to the principal techniques used to study the interactions of proteins and ligands. This second volume covers the major spectroscopic methods: FTIR, Raman, and fluorescence spectroscopy; circular dichroism, NMR, mass spectrometry, atomic force microscopy, and the use of paramagnetic probes. There are also chapters on X-ray crystallography and molecular modelling. Hydrodynamic and calorimetric techniques are covered in volume one. Both volumes are available individually, or as a set. Both volumes are written from a practical standpoint to be applicable to both academic and industrial scientists wishing to characterize protein-ligand systems by using a multi-disciplinary approach.