Toxicology of Metals: Biochemical Aspects (Handbook of Experimental Pharmacology)

This volume focusses on new advances in topics of current interest in metal toxicology. These include mechanisms regarding health effects that are important in riskassessment for human health. The book also has chapters on emerging conceptual problems including resistance to metal toxicity effects on gene expression. Furthermore, principles regarding drug-chelation of metals, the potential use of prophyrins as indicators of metal exposure and toxicity are presented. In addition, the toxicology of specific metals of major public health concern are discussed in depth, such as mercury, aluminum, arsenic, chromium, and cadmium. The topics presented will be of interest to basic scientists as well as public health administrators.