Huntington's Disease (Major Problems in Neurology, Vol 22)

Huntington's chorea is a rare hereditary disease characterized by quick involuntary movements, speech disturbances and mental deterioration caused by degenerative changes in the cerebral cortex and basal ganglia. Professor Harper and his colleagues have been working on this disease for the past 15 to 20 years and this monograph brings together the results of their findings over this period. The book is characterized by a multi-disciplinary approach covering underlying molecular biology, clinical neurology, psychiatric aspects and counselling of families. Professor Harper is a leading world authority on Huntington's Chorea and is also the author of an earlier monograph in the same series, on myotonic dystrophy.