Angiogenesis in Health and Disease: Basic Mechanisms and Clinical Applications

Outlines strategies for stimulating capillary formation in hypoxia and ischemia and inhibiting it in cancer, diabetes, and chronic inflammation.
This state-of-the-science reference highlights recent progress in the ways to promote formation of new blood vessels in ischemic/hypoxic tissue and the means to stifle capillary growth and development in solid tumors, diabetic retinopathy, and chronic immuno/inflammatory disorders such as rheumatoid arthritis and psoriasis.
Emphasizes practical clinical applications derived from the latest angiogenesis research.
Written by over 80 leading international experts, Angiogenesis in Health and Disease

examines new angiogenic regulators such as angiopoietins and TIE-receptors

describes angiogenic genes such as thymosine B-4, EDG-1, and ARNT proteins

analyzes the role of vascular endothelial growth factor (VEGF) in capillary sprouting

investigates behaviors of endogenous agents of angiogenesis, including cytokines, hormones, chemokines, and peptide and hematopoietic growth factors

explores mechanisms for ameliorating or preventing vascular occlusive disease by induction of collateral artery growth

explains differences in conditions that prompt angiogenesis and arteriogenesis

reviews transgenic and knock-out mice, receptor protein mutations, and other emerging technologies

evaluates angiogenic inhibitors such as angiostatin and endostatin

and more!
Containing over 3000 references, tables, drawings, and photographs, Angiogenesis in Health and Disease deserves a prominent place on the bookshelves of cardiologists, oncologists, physiologists, hematologists, molecular and cell biologists, biochemists, pharmacologists, rheumatologists, vascular surgeons, and upper-level undergraduate, graduate, and medical school students in these disciplines.