Mutagenesis of the Mouse Genome (Georgia Genetics Review)

Mutagenesis of the Mouse Genome focuses on articles relevant to mouse chemical mutagenesis, and is dedicated to the memory of the mutagenesis pioneer, William L. Russell. Monica Justice provides an overview of the history of the Human Genome Project and use of the mouse as the primary organism for the functional annotation of the mammalian genome. With special articles by Jean-Louis Guenet describing the history and development of mouse chemical mutagenesis, Liane Russell analyzing decades of data on DNA damage after chemical treatment, Steven Barthold describing how environment can affect mouse phenotypes, Miriam Meisler summarizing the power of allelic series, Molly Bogue describing the variation in mouse inbred strains, and Mark Strivens and Janan Eppig showing how informatics tools can aid in functional analysis, this book is designed to be a handbook and reference guide for mouse genetics in the post-genome era.