Heme Oxygenase in Biology and Medicine

The recent convergence of research in stem cell biology, leukemic cell genetics, and drug discovery has provided remarkable insight into pathogenesis and treatment of leukemia and lymphoma. These insights have led to the new therapeutic approaches involving the manipulation of molecular and/or biochemical pathways in leukemia cells. Nonetheless, effective treatment and cures for these blood-related diseases remains, in many cases elusive. This symposium is designed to integrate recent knowledge regarding the basic cellular and molecular biology of leukemia and lymphoma with new approaches to diagnosis and therapy. To this end, a translation research (laboratory to bedside) approach will be encouraged throughout the meeting, with discussions covering new mechanisms regulating hematopoietic cell development, recent new data from clinical trails of new molecular therapeutics, and newly emerging directions in diagnosis. The symposium will bring together basic, translational, and clinical investigators in a meeting aimed at developing potential collaborative interaction. The intension is to provide new insights into the molecular targets for the treatment of blood-related cancers