Boys Over Flowers (Hana Yori Dango), Vol. 1

This classic shojo is featured in a 51-episode anime series. When her only friend, Makiko, accidentally offends F4 leader Tsukasa, Tsukushi boldly defends her. Enraged, Tsukasa puts the dreaded red tag in Tsukushi's locker — a sign that she is now a target for the abuse of the F4 gang and the entire school. But when Tsukushi fights the gang with their own weapon, Tsukasa finds himself falling for her!