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📖 Description
Biotransformations have developed into an important tool of organic synthesis. Most synthetic sequences will benefit from the use of a biotransformation step, and the use of multiple enzyme single pot reactions enables several steps to be telescoped together. Volumes 8a and b provide a comprehensive guide to the established and emerging uses of enzymes. Each chapter is devoted to a single class of transformation so that the competing possibilities can be readily compared, and there is a strong emphasis on practical and reliable reactions. Topics included in Volume 8a are: Perspectives/ Practical Aspects/ Lipases/ Esterases/ Cleavage of Amide Bonds/ Nitriles/ Alkaloids/ Yeast/ Alcohol Dehydrogenases/ Hydroxylation and Dihydroxylation/ Flavin Monooxygenases Major topics of Volume 8b: Phosphorylation/ C-C Bond Formation/ Formation of Glycoside Bonds/ Synthetic Applications