Phospholipid interactions with Sterols and Peptides: Calorimetric and Molecular Acoustic study of phosholipid - Sterol and Phospholipid - Peptide Interactions

In this study, the influence of the sterol side chain and ring structure on the volumetric properties of the lipid bilayer system was investigated using calorimetry and molecular acoustics. In addition, the influence of peptides, gramicidin and melittin incorporation into the phospholipid bilayer was studied.Peptide insertion into DPPC bilayer has significant influence on the lipid bilayer structure, temperature, and pressure dependence phase behaviour.