Biologically Important Quinazoline ''Ones'' and ''Thions''

These novel ‘‘one’’ and ‘‘thione’’ derivatives were synthesized by using established methods and were characterized by IR, 1H NMR and Mass spectroscopy in order to confirm their formation. These compounds were synthesized to screen for their antibacterial, antifungal and antitubercular activities. The compounds were found to be potent against Gram +ve, Gram –ve bacterial, fungal and H37Ra strains. In the view of result the most active compounds are carrying thiourea and its dominating urea derivatives.