Metal Complexes in Biological System

Aim to design artificial metallonucleases and therapeutic applicable molecules (antibacterial and antitumor), we planned to synthesize metal complexes of gold and copper metal ions and tested for their diverse biological activity like DNA interaction, SOD mimic, cytotoxic and antibacterial activity. The complexes as drug work in one of the two ways: some use a process called redox chemistry to steal electrons from the bonds holding the target molecules together. Others use hydrolysis, meaning that they breakdown the target’s chemical waterproofing, so that the water that is naturally present in a cell dissolves the target.