Dna Structure & Function

Key Features Special Features Explains basic DNA Structure and function clearly and simply Contains up-to-date coverage of cruciforms, Z-DNA, triplex DNA, and other DNA conformations Discusses DNA-protein interactions, chromosomal organization, and biological implications of structure Highlights key experiments and ideas within boxed sections Illustrated with 150 diagrams and figures that convey structural and experimental concepts Description DNA Structure and Function , a timely and comprehensive resource, is intended for any student or scientist interested in DNA structure and its biological implications. The book provides a simple yet comprehensive introduction to nearly all aspects of DNA structure. It also explains current ideas on the biological significance of classic and alternative DNA conformations. Suitable for graduate courses on DNA structure and nucleic acids, the text is also excellent supplemental reading for courses in general biochemistry, molecular biology, and genetics. Readership Graduate and advanced undergraduate students and researchers in molecular biology, biochemistry, genetics, microbiology, biophysics, chemistry, cell biology, and biotechnology. Quotes @qu:"Well written, authoritative, organized and comprehensive coverage of a rapidly developing subject. It is a very impressive compilation and one which will be useful to a wide audience. The book introduces the reader to the complex mosaic of DNA architecture-the A, B, H, Z, supercoiled, and the cruciform structures of DNA. The interconversion of these structures, together with the interaction with sequence and/or structure specific proteins provides the basis for the delicate orchestration of the flow of the genetic message within the cell. In vitro , [as well as] in vivo experiments are presented. The DNA structural findings lead one into the specific relevance of these forms in the vital functional processes-replication, transcription, genetic recombination and DNA repair-which