Production of penicillic acid by Aspergillus sclerotiorum CGF [An article from: Bioresource Technology]

This digital document is a journal article from Bioresource Technology, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
The production of penicillic acid by Aspergillus sclerotiorum CGF for the biocontrol of Phytophthora disease was investigated in submerged fermentation using media composed of different nutrients. Soluble starch was found to be the most effective substrate among the carbon sources used, and produced the highest penicillic acid concentration of 2.98mgml^-^1. When organic nitrogen sources were used, pharmamedia, yeast extract, and polypeptone-S were found to be suitable organic nitrogen sources (2.46-2.71mgml^-^1). The production of penicillic acid was not detected in when inorganic nitrogen sources were used. Only Na"2HPO"4, among the metal ions and phosphate salts tested, increased the production of penicillic acid (~20%). When A. sclerotiorum CGF was cultured in optimal medium [8.0% (w/v) soluble starch, 0.6% (w/v) yeast extract, and 0.3% (w/v) Na"2HPO"4], maximum penicillic acid concentration (~9.40mgml^-^1) and cell mass (~17.4gl^-^1) were obtained after 12 days.