Influence of platinum, palladium and rhodium as compared with cadmium, nickel and chromium on cell viability and oxidative stress in human bronchial ... [An article from: Environment International]

This digital document is a journal article from Environment International, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
The platinum group elements (PGE) Pt, Pd and Rh are increasingly emitted into the environment by automobile catalytic converters. Whereas the biological availability of PGE to plants and animals has been demonstrated, only few studies concentrate on the influence of PGE on a cellular level. The effects of Pt, Pd and Rh compared with Cd, Ni and Cr on cell viability and oxidative stress response using soluble metal salts were studied in the human bronchial epithelial cell line BEAS-2B. Whilst Rh(III) showed little influence, both Pt(II) and Pt(IV) as well as Pd(II) had significant effects on cell viability at levels comparable to Cd(II) and Cr(VI). Arranging metal species in order of increasing toxicity as determined by LC"5"0 yields: Rh(III)=1.2 mmol/L