Antimicrobial activity of marine organisms collected off the coast of South East India [An article from: Journal of Experimental Marine Biology and Ecology]

This digital document is a journal article from Journal of Experimental Marine Biology and Ecology, published by Elsevier in 2004. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
In vitro antimicrobial screening of nine marine sponges (Porifera) and two seaweeds, collected from south east coast of India, against selected clinical isolates of bacteria and fungi was conducted in this study. Methanolic extracts of all the marine organisms demonstrated activity against one or more of microbes tested. Sigmadocia carnosa was the most active exhibiting a broad spectrum antimicrobial activity against each of the microbe tested with the exception of Fusarium species. Contrary to this, the genus Echinogorgia did not show any detectable bactericidal activity but, Echninogorgia reticulata was weakly fungicidal against Rhodotorula species and E. compecta against Fusarium and Nocardia species. Considerable antibacterial activity was exhibited by Haliclona cribricutis and Chrotella australiensis against Klebsiella species and Vibrio cholerae, respectively. Petrocia testudinaria showed equally good activity against the bacterium V. chlorae and the fungus Cryptococcus neoformans. The sponges Callyspongia fibrosa, Ircinia species and the seaweed Stoecheospermum margilatum are totally inactive against fungi. The extracts showing good antimicrobial activity are undergoing further analysis to identify the active constituents.