![Multiresidue analysis of anabolic compounds in bovine hair by gas chromatography-tandem mass spectrometry [An article from: Analytica Chimica Acta]](https://www.ebooknetworking.net/books/B00/0RR/bigB000RR00Q0.jpg)
Multiresidue analysis of anabolic compounds in bovine hair by gas chromatography-tandem mass spectrometry [An article from: Analytica Chimica Acta]
Book Details
PublisherElsevier
ISBN / ASINB000RR00Q0
ISBN-13978B000RR00Q2
AvailabilityAvailable for download now
MarketplaceUnited States 🇺🇸
Description
This digital document is a journal article from Analytica Chimica Acta, published by Elsevier in 2004. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.
Description:
A rapid and specific multiresidue method was developed to perform screening and confirmation of 15 anabolics steroids in bovine hair, namely: dienestrol, DES, hexestrol, 17@a- and 17@b-estradiol, 17@a- and 17@b-19-nortestosterone, 17@a- and 17@b-boldenone, testosterone (@b) and epitestosterone (@a), ethynylestradiol, @a-methyltestosterone, and @a- and @b-Zearalanol. After methanolic and solid-phase extraction, trimethylsilyl derivatization (TMS) was performed and the derivatized extracts submitted to GC-MS-MS analysis. TMS derivatives of the studied hormones yielded specific MS-MS fragmentation with a high abundance for ions selected in the screening procedure. Validation was performed regarding qualitative parameters: decision limit (CC@a), detection capability (CC@b) and specificity. For confirmation, European union criteria 2002/657/EC were considered. Detection capability ranged between 1.0 and 10.0ngg^-^1 depending on the compound.
Description:
A rapid and specific multiresidue method was developed to perform screening and confirmation of 15 anabolics steroids in bovine hair, namely: dienestrol, DES, hexestrol, 17@a- and 17@b-estradiol, 17@a- and 17@b-19-nortestosterone, 17@a- and 17@b-boldenone, testosterone (@b) and epitestosterone (@a), ethynylestradiol, @a-methyltestosterone, and @a- and @b-Zearalanol. After methanolic and solid-phase extraction, trimethylsilyl derivatization (TMS) was performed and the derivatized extracts submitted to GC-MS-MS analysis. TMS derivatives of the studied hormones yielded specific MS-MS fragmentation with a high abundance for ions selected in the screening procedure. Validation was performed regarding qualitative parameters: decision limit (CC@a), detection capability (CC@b) and specificity. For confirmation, European union criteria 2002/657/EC were considered. Detection capability ranged between 1.0 and 10.0ngg^-^1 depending on the compound.
