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Determination of fenoterol hydrobromide by sequential injection analysis with spectrophotometric detection [An article from: Analytica Chimica Acta]
Book Details
PublisherElsevier
ISBN / ASINB000RR04B6
ISBN-13978B000RR04B8
AvailabilityAvailable for download now
MarketplaceUnited States 🇺🇸
Description
This digital document is a journal article from Analytica Chimica Acta, published by Elsevier in 2004. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.
Description:
A rapid, economical and automated sequential injection spectrophotometric determination of the phenolic sympathomimetic drug, fenoterol hydrobromide, is reported. The method is based on the reaction of fenoterol hydrobromide with 4-aminoantipyrine and potassium hexacyanoferrate and the absorbance of the colored product monitored at 505nm. Chemical as well as physical SIA parameters that affect the signal response have been optimized in order to get better sensitivity, higher sampling rate and better reagent economy. Using the optimized parameters, a linear relationship between the relative peak height and concentration was obtained in the range 0.5-40mgL^-^1. The detection limit (as 3@s value) was 0.1mgL^-^1 and precision was 1.8 and 1.6% at 2 and 5mgL^-^1, respectively. As compared to previous works, wide linear range, low detection limit, and highly economical reagent consumption are the advantages of our method.
Description:
A rapid, economical and automated sequential injection spectrophotometric determination of the phenolic sympathomimetic drug, fenoterol hydrobromide, is reported. The method is based on the reaction of fenoterol hydrobromide with 4-aminoantipyrine and potassium hexacyanoferrate and the absorbance of the colored product monitored at 505nm. Chemical as well as physical SIA parameters that affect the signal response have been optimized in order to get better sensitivity, higher sampling rate and better reagent economy. Using the optimized parameters, a linear relationship between the relative peak height and concentration was obtained in the range 0.5-40mgL^-^1. The detection limit (as 3@s value) was 0.1mgL^-^1 and precision was 1.8 and 1.6% at 2 and 5mgL^-^1, respectively. As compared to previous works, wide linear range, low detection limit, and highly economical reagent consumption are the advantages of our method.
