Fabrication of nano/microfiber scaffolds using a combination of rapid prototyping and electrospinning systems.(Report): An article from: Polymer Engineering and Science
Book Details
Author(s)Su A. Park, Hyo Joo Kim, Su Hee Lee, Jun Hee Lee, Hyung Keun Kim, Taek Rim Yoon, WanDoo Kim
PublisherSociety of Plastics Engineers, Inc.
ISBN / ASINB005MMNRMO
ISBN-13978B005MMNRM7
MarketplaceFrance 🇫🇷
Description
This digital document is an article from Polymer Engineering and Science, published by Society of Plastics Engineers, Inc. on September 1, 2011. The length of the article is 3131 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available immediately after purchase. You can view it with any web browser.
From the author: Tissue-engineered scaffolds require an adequate three-dimensional (3-D) structure for cell growth and attachment. Solid freeform fabrication can provide the interconnected pore to induce the cell ingrowth, and electrospinning technique can make the nanofiber web with high surface for cell attachment. In this study, 3-D polycaprolactone (PCL) scaffolds were fabricated using a rapid prototyping plotting system coupled with an electrospinning apparatus. Scanning electron micrographs showed that these hybrid scaffolds had a regular microfiber structure with interconnected pores and a nanofiber distribution appropriate for cell attachment. Scaffolds were seeded with MG63 cells for in vitro study and implanted in the tibia of rabbit for in vivo study. The resulting structure also facilitated cell adhesion, proliferation, and differentiation as evidenced by biochemical analyses and confocal microscopy. The hybrid scaffolds also exhibited good biocompatibility and osteoconductivity in animal studies. POLYM. ENG. SCI., 51:1883-1890, 2011. [c] 2011 Society of Plastics Engineers
Citation Details
Title: Fabrication of nano/microfiber scaffolds using a combination of rapid prototyping and electrospinning systems.(Report)
Author: Su A. Park
Publication:Polymer Engineering and Science (Magazine/Journal)
Date: September 1, 2011
Publisher: Society of Plastics Engineers, Inc.
Volume: 51 Issue: 9 Page: 1883(8)
Article Type: Report
Distributed by Gale, a part of Cengage Learning
From the author: Tissue-engineered scaffolds require an adequate three-dimensional (3-D) structure for cell growth and attachment. Solid freeform fabrication can provide the interconnected pore to induce the cell ingrowth, and electrospinning technique can make the nanofiber web with high surface for cell attachment. In this study, 3-D polycaprolactone (PCL) scaffolds were fabricated using a rapid prototyping plotting system coupled with an electrospinning apparatus. Scanning electron micrographs showed that these hybrid scaffolds had a regular microfiber structure with interconnected pores and a nanofiber distribution appropriate for cell attachment. Scaffolds were seeded with MG63 cells for in vitro study and implanted in the tibia of rabbit for in vivo study. The resulting structure also facilitated cell adhesion, proliferation, and differentiation as evidenced by biochemical analyses and confocal microscopy. The hybrid scaffolds also exhibited good biocompatibility and osteoconductivity in animal studies. POLYM. ENG. SCI., 51:1883-1890, 2011. [c] 2011 Society of Plastics Engineers
Citation Details
Title: Fabrication of nano/microfiber scaffolds using a combination of rapid prototyping and electrospinning systems.(Report)
Author: Su A. Park
Publication:Polymer Engineering and Science (Magazine/Journal)
Date: September 1, 2011
Publisher: Society of Plastics Engineers, Inc.
Volume: 51 Issue: 9 Page: 1883(8)
Article Type: Report
Distributed by Gale, a part of Cengage Learning
