Studies on the performance of the conducting polymer-based molecular release system.(Report): An article from: Polymer Engineering and Science

This digital document is an article from Polymer Engineering and Science, published by Society of Plastics Engineers, Inc. on October 1, 2011. The length of the article is 7230 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available immediately after purchase. You can view it with any web browser.

From the author: 'Conducting polymeric (CP) membrane based controlled molecular release under applied electrical potential' is an important futuristic application in 'drug delivery'. A validated Poisson-Nernst-Planck based framework has been used in this study for the purpose of performance mapping for such a system. Leaking of the molecules during loading time and retention of molecules at the end of each voltage cycle have been identified here as the major bottlenecks in the use of this system in a sustainable basis. Peak flux of ionic molecules delivered is a key objective to be maximized along with minimum retention and leakage. Results reveal that parameters like time of voltage span, effective diffusivity, polymer film thickness need to be tightly maintained. At the same time, a wide variety of CP-drug combinations can be acceptable. This opens the possibilities of utilizing this system for large range of therapeutic applications for controlled drug delivery. POLYM. ENG. SCI., 51:2001-2012, 2011. [c]2011 Society of Plastics Engineers

Citation Details
Title: Studies on the performance of the conducting polymer-based molecular release system.(Report)
Author: Saptarshi Majumdar
Publication:Polymer Engineering and Science (Magazine/Journal)
Date: October 1, 2011
Publisher: Society of Plastics Engineers, Inc.
Volume: 51 Issue: 10 Page: 2001(12)

Article Type: Report

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