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Study of AP Endonuclease, a DNA Repair Enzyme in Gallbladder Carcinoma (Paperback) - Common

Name: Study of AP Endonuclease, a DNA Repair Enzyme in Gallbladder Carcinoma (Paperback) - Common
Author: By (author) Prashant Chandra Das, By (author) M.J. Raman By (author) Vijay Shukla
ISBN: 978B00EQCBEL2

AuthorBy (author) Prashant Chandra Das, By (author) M.J. Raman By (author) Vijay Shukla

PublisherLap Lambert Academic Publishing AG & Co Kg

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Book Details

Author(s)By (author) Prashant Chandra Das, By (author) M.J. Raman By (author) Vijay Shukla

PublisherLap Lambert Academic Publishing AG & Co Kg

ISBN / ASINB00EQCBEL2

ISBN-13978B00EQCBEL2

Sales Rank99,999,999

MarketplaceUnited States 🇺🇸

Description

The human AP-endonuclease (APE1/Ref-1), an essential multifunctional protein, plays a central role in the repair of oxidative base damage via the DNA base excision repair (BER) pathway. The mammalian AP-endonuclease (APE1) overexpression is often observed in tumor cells, and confers resistance to various anticancer drugs; its downregulation sensitizes tumor cells to those agents via induction of a...