Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components: Chapter 12. Perspectives and Key Factors Affecting the Use of ... Multidrug-Resistant Gram-Negative Bacteria

In today’s world, multidrug resistance appears to be one of the major health problems; however, screening, discovering and presenting novel effectual phytochemicals from medicinal plants have provided a promising outlook. Phytomedicines have been used for treating diseases and infections since time immemorial, but identifying new phytochemicals and effectual treatment strategies are essential in the fight against multidrug-resistant bacteria. Currently, isolated compounds such as α-mangostin, carnosic acid, epigallocatechin gallate, linalool, myricetin, novoimanin, α-terpineol, and totarol, have exhibited synergistic activity with antibiotics against resistant bacteria. This chapter presents information on multidrug-resistant Gram-negative bacteria and the use of herbal extracts against them.